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New York Times: In a New Approach to Fighting Disease, Helpful Genetic Mutations Are Sought

December 28, 2014

New York Times: In a New Approach to Fighting Disease, Helpful Genetic Mutations Are Sought

Doug Whitney should have died years ago. The 65-year-old resident of Port Orchard, Wash., has a devastating gene mutation that — according to the medical literature — causes early onset Alzheimer’s disease in everyone who inherits it.

The mutation killed Mr. Whitney’s mother and nine of her 13 siblings, and it killed Mr. Whitney’s older brother. Every one of them began showing symptoms when they were in their 40s. Most died by their mid-50s. In the next generation, six cousins died of early onset Alzheimer’s, and two others are in the final stages of the disease. One of his cousin’s children also has Alzheimer’s.

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