Patients as Research Partners
Biomedical research needs to empower patients with the voice and the tools they need to manage their health, understand their disease and partner in research.
The BRIDGE platform and its first pilot community
projects will provide successes and lessons including…
how to bring the open-source movement to medical discovery.
how to activate citizen-patients for participation in medical research.
how to incentivize scientists to share their data and disease models to accelerate biomedical discovery.
The past few decades have seen the emergence of affordable genomics, sensors, mobile phone cameras and apps and online tools that for the first time allow each of us to collect data on ourselves precisely and frequently. Although the understanding of how to use mobile sensor data is in its infancy, these tools make it possible to generate detailed natural history timelines of individual health and disease. Sage’s mission with Bridge is to create open mobile health data sets that can be used by any qualified researcher to improve their understanding of human diseases.
Toward this goal, Sage Bionetworks, with support from the Robert Wood Johnson Foundation, is building BRIDGE a web-based, open-source platform that will allow patients to provide their data and insights as research partners on the health problems that matter most to them.
Current BRIDGE Studies
We expect to open enrollment for these studies in the first half of 2015.
The Parkinson’s Disease Bridge Study: Parkinson’s Disease is characterized by neuro-motor defects that affect gait, posture, voice, and manual dexterity. Although there is a long gradual decline in function as the disease progresses, patients often report significant fluctuations in short term severity of the disease, for reasons that are not well understood. This study will use microphone, acclerometer, and touch-screen sensors in a mobile app to measure these fluctuations more consistently over time, and explore correlations with environmental factors such as sleep and exercise.
The Breast Cancer Survivor Bridge Study: Months to years after treatment, many women report disturbances in mood, cognitive function, and energy level which fluctuate over days, weeks and months. This study is designed to look at the long term side effects of chemotherapy. It will explore the intersection of these experiences with environmental factors such as the quality and quantity of sleep and exercise to learn how symptoms can be more effectively managed by survivors.